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1

In vitro exposure of tracheobronchial epithelial cells and of tracheal explants to ozone

Brian K. Tarkington, Reen Wu, Wei-Min Sun, Kristen J. Nikula, Dennis W. Wilson, Jerold A. Last

Journal:

Année:

1994

Langue:

english

Fichier:

PDF, 2.88 MB

english, 1994

2

Apoptosis is a pathway responsible for the resolution of endotoxin-induced alveolar type II cell hyperplasia in the rat

JOHANNES TESFAIGZI, MARCY B. WOOD, NEIL F. JOHNSON, KRISTEN J. NIKULA

Journal:

International Journal of Experimental Pathology

Année:

1998

Langue:

english

Fichier:

PDF, 415 KB

english, 1998

3

Experimental hypersensitivity pneumonitis: influence of Th2 bias

Mark Schuyler, Katherine Gott, Vesta Mapel, Amy Cherne, Kristen J. Nikula

Journal:

International Journal of Experimental Pathology

Année:

1999

Langue:

english

Fichier:

PDF, 368 KB

english, 1999

4

Pulmonary delivery of nanoparticles of insoluble, iodinated CT x-ray contrast agents to lung draining lymph nodes in dogs

Gregory L. McIntire, Edward R. Bacon, John L. Toner, Joel B. Cornacoff, Patricia E. Losco, Kathleen J. Illig, Kristen J. Nikula, Bruce A. Muggenburg, Loren Ketai

Journal:

Journal of Pharmaceutical Sciences

Année:

1998

Langue:

english

Fichier:

PDF, 79 KB

english, 1998

5

Nasal Cytochrome P450 2A: Identification, Regional Localization, and Metabolic Activity toward Hexamethylphosphoramide, a Known Nasal Carcinogen

Janice R. Thornton-Manning, Kristen J. Nikula, Jon A. Hotchkiss, Kelly J. Avila, Kevin D. Rohrbacher, Xinxin Ding, Alan R. Dahl

Journal:

Toxicology and Applied Pharmacology

Année:

1997

Langue:

english

Fichier:

PDF, 670 KB

english, 1997

6

In vitro evidence of cellular adaptation to ozone toxicity in the rat trachea

Kristen J. Nikula, Dennis W. Wilson, Donald L. Dungworth, Charles G. Plopper

Journal:

Toxicology and Applied Pharmacology

Année:

1988

Langue:

english

Fichier:

PDF, 3.39 MB

english, 1988

7

C-122, a novel antagonist of serotonin receptor 5-HT2B, prevents monocrotaline-induced pulmonary arterial hypertension in rats

David A. Zopf, Liomar A.A. das Neves, Kristen J. Nikula, Jinbao Huang, Peter B. Senese, Michael R. Gralinski

Journal:

European Journal of Pharmacology

Année:

2011

Langue:

english

Fichier:

PDF, 1.01 MB

english, 2011

8

Lung Tissue Responses and Sites of Particle Retention Differ between Rats and Cynomolgus Monkeys Exposed Chronically to Diesel Exhaust and Coal Dust

Kristen J. Nikula, Kelly J. Avila, William C. Griffith, Joe L. Mauderly

Journal:

Fundamental and Applied Toxicology

Année:

1997

Langue:

english

Fichier:

PDF, 2.58 MB

english, 1997

9

Failure of cigarette smoke to induce or promote lung cancer in the A/J mouse

Gregory L. Finch, Kristen J. Nikula, Steven A. Belinsky, Edward B. Barr, Gary D. Stoner, John F. Lechner

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 702 KB

english, 1996

10

Absence of p53 gene mutations in rat colon carcinomas induced through the synergistic interaction between methylazoxymethanol and X-irradiation

Narayan Shivapurkar, Kristen J. Nikula, Takuji Tanaka, Zhao Cheng Tang, Oliver Alabaster

Journal:

Année:

1997

Langue:

english

Fichier:

PDF, 4.21 MB

english, 1997

11

A microassay for measuring cytosine DNA methyltransferase activity during tumor progression

Steven A. Belinsky, Kristen J. Nikula, Stephen B. Baylin, Jean-pierre Issa

Journal:

Toxicology Letters

Année:

1995

Langue:

english

Fichier:

PDF, 587 KB

english, 1995

12

Ultraviolet Radiation, Solar Dermatosis, and Cutaneous Neoplasia in Beagle Dogs

Kristen J. Nikula, Stephen A. Benjamin, George M. Angleton, William J. Saunders and A. Clair Lee

Journal:

Radiation Research

Année:

1992

Langue:

english

Fichier:

PDF, 1.14 MB

english, 1992

13

CT imaging of intrathoracic lymph nodes in dogs with bronchoscopically administered iodinated nanoparticles

Ketai, Loren H., Muggenberg, Bruce A., McIntire, Gregory L., Bacon, Edward R., Rosenberg, Robert, Losco, Patricia E., Toner, John L., Nikula, Kristen J., Haley, Patrick

Journal:

Academic Radiology

Année:

1999

Langue:

english

Fichier:

PDF, 1.82 MB

english, 1999

14

Increased Cytosine DNA-Methyltransferase Activity is Target-Cell-Specific and an Early Event in Lung Cancer

Steven A. Belinsky, Kristen J. Nikula, Stephen B. Baylin and Jean-Pierre J. Issa

Journal:

Proceedings of the National Academy of Sciences

Année:

1996

Langue:

english

Fichier:

PDF, 1.30 MB

english, 1996

15

Aberrant Methylation of p16INK4aIs an Early Event in Lung Cancer and a Potential Biomarker for Early Diagnosis

Steven A. Belinsky, Kristen J. Nikula, William A. Palmisano, Ruth Michels, Geno Saccomanno, Edward Gabrielson, Stephen B. Baylin and James G. Herman

Journal:

Proceedings of the National Academy of Sciences

Année:

1998

Langue:

english

Fichier:

PDF, 1.84 MB

english, 1998

16

Supplement 4 || Alterations in the K-ras and p53 Genes in Rat Lung Tumors

Steven A. Belinsky, Deborah S. Swafford, Gregory L. Finch, Charles E. Mitchell, Gregory Kelly, Fletcher F. Hahn, Marshall W. Anderson and Kristen J. Nikula

Journal:

Environmental Health Perspectives

Année:

1997

Langue:

english

Fichier:

PDF, 1.09 MB

english, 1997

17

Supplement 5: Particle Toxicity || Sites of Particle Retention and Lung Tissue Responses to Chronically Inhaled Diesel Exhaust and Coal Dust in Rats and Cynomolgus Monkeys

Kristen J. Nikula, Kelly J. Avila, William C. Griffith and Joe L. Mauderly

Journal:

Environmental Health Perspectives

Année:

1997

Langue:

english

Fichier:

PDF, 384 KB

english, 1997

18

Influence of Exposure Concentration or Dose on the Distribution of Particulate Material in Rat and Human Lungs

Kristen J. Nikula, Val Vallyathan, Francis H. Y. Green and Fletcher F. Hahn

Journal:

Environmental Health Perspectives

Année:

2001

Langue:

english

Fichier:

PDF, 3.05 MB

english, 2001

19

Supplement 5 || Animal Models of Beryllium-Induced Lung Disease

Gregory L. Finch, Mark D. Hoover, Fletcher F. Hahn, Kristen J. Nikula, Steven A. Belinsky, Patrick J. Haley and William C. Griffith

Journal:

Environmental Health Perspectives

Année:

1996

Langue:

english

Fichier:

PDF, 358 KB

english, 1996

20

Analysis of the K-ras and p53 Pathways in X-Ray-Induced Lung Tumors in the Rat

Steven A. Belinsky, Susan K. Middleton, Steven M. Picksley, Fletcher F. Hahn and Kristen J. Nikula

Journal:

Radiation Research

Année:

1996

Langue:

english

Fichier:

PDF, 1.95 MB

english, 1996

21

Biological Effects of${}^{137}{\rm CsCl}$Injected in Beagle Dogs

Kristen J. Nikula, Bruce A. Muggenburg, I-Yiin Chang, William C. Griffith, Fletcher F. Hahn and Bruce B. Boecker

Journal:

Radiation Research

Année:

1995

Langue:

english

Fichier:

PDF, 2.63 MB

english, 1995

22

RAT LUNG TUMORS INDUCED BY EXPOSURE TO SELECTED POORLY SOLUBLE NONFIBROUS PARTICLES

Nikula, Kristen J.

Journal:

Inhalation Toxicology

Année:

2000

Langue:

english

Fichier:

PDF, 310 KB

english, 2000

23

Effects of Cigarette Smoke on the Glutathione Status of the Upper and Lower Respiratory Tract of Rats

Maples, Kirk R., Nikula, Kristen J., Chen, Bean T., Finch, Gregory L., Griffith, William C., Harkema, Jack R.

Journal:

Inhalation Toxicology

Année:

1993

Langue:

english

Fichier:

PDF, 940 KB

english, 1993

24

A Reliable Method Not Requiring Sophisticated Instrumentation for Isolation of a High-Purity Population of Adult Rat Type II Cells

Scott, Gary G., Nikula, Kristen J., Waide, James J., Henderson, Rogene F.

Journal:

Toxicology Mechanisms and Methods

Année:

1996

Langue:

english

Fichier:

PDF, 588 KB

english, 1996

25

Recommendation of Optimal Method for Formalin Fixation of Rodent Lungs in Routine Toxicology Studies

Renne, Roger, Fouillet, Xavier, Maurer, James, Assaad, Ayaad, Morgan, Kevin, Hahn, Fletcher, Nikula, Kristen, Gillet, Nancy, Copley, Marion

Journal:

Toxicologic Pathology

Année:

2001

Langue:

english

Fichier:

PDF, 71 KB

english, 2001

26

EFFECTS OF CIGARETTE SMOKE EXPOSURE AND CESSATION ON INFLAMMATORY CELLS AND MATRIX METALLOPROTEINASE ACTIVITY IN MICE

Seagrave, JeanClare, Barr, Edward B., March, Thomas H., Nikula, Kristen J.

Journal:

Experimental Lung Research

Année:

2004

Langue:

english

Fichier:

PDF, 1.56 MB

english, 2004

27

Response of Rat Tracheal Epithelium to Ozone and Oxygen Exposure in Vitro

NIKULA, KRISTEN J., WILSON, DENNIS W.

Journal:

Toxicological Sciences

Année:

1990

Langue:

english

Fichier:

PDF, 1.79 MB

english, 1990

28

Lung Tissue Responses and Sites of Particle Retention Differ between Rats and Cynomolgus Monkeys Exposed Chronically to Diesel Exhaust and Coal Dust

Nikula, Kristen J., Avila, Kelly J., Griffith, William C., Mauderly, Joe L.

Journal:

Toxicological Sciences

Année:

1997

Langue:

english

Fichier:

PDF, 7.79 MB

english, 1997

29

Effects of Strain and Treatment with Inhaled All-Trans-Retinoic Acid on Cigarette Smoke-Induced Pulmonary Emphysema in Mice

March, Thomas, Bowen, Larry, Finch, Gregory, Nikula, Kristen, Wayne, Bonnie, Hobbs, Charles

Journal:

COPD Journal of Chronic Obstructive Pulmonary Disease

Année:

2005

Langue:

english

Fichier:

PDF, 4.71 MB

english, 2005

30

Effects of Strain and Treatment with Inhaled All- Trans -Retinoic Acid on Cigarette Smoke-Induced Pulmonary Emphysema in Mice

March, Thomas, Bowen, Larry, Finch, Gregory, Nikula, Kristen, Wayne, Bonnie, Hobbs, Charles

Journal:

COPD Journal of Chronic Obstructive Pulmonary Disease

Année:

2005

Langue:

english

Fichier:

PDF, 4.71 MB

english, 2005

31

Low frequency of alterations in p53 , K- ras , and mdm2 in rat lung neoplasms induced by diesel exhaust or carbon black

Swafford, Deborah S., Nikula, Kristen J., Mitchell, Charles E., Belinsky, Steven A.

Journal:

Année:

1995

Langue:

english

Fichier:

PDF, 3.77 MB

english, 1995

32

Biological Effects of${}^{137}{\rm CsCl}$Injected in Beagle Dogs of Different Ages

Kristen J. Nikula, Bruce A. Muggenburg, William C. Griffith, William W. Carlton, Thomas E. Fritz and Bruce B. Boecker

Journal:

Radiation Research

Année:

1996

Langue:

english

Fichier:

PDF, 2.06 MB

english, 1996

33

A Mouse Model of Cigarette Smoke-Induced Emphysema

Nikula, Kristen J., March, Thomas H., Seagrave, J., Finch, G., Barr, E., Ménache, M., Hahn, F., Hobbs, C.

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 173 KB

english, 2000

34

Intermittent convection-enhanced delivery of GDNF into rhesus monkey putamen: absence of local or cerebellar toxicity

Luz, Matthias, Allen, Philip C., Bringas, John, Boiko, Chris, Stockinger, Diane E., Nikula, Kristen J., Lewis, Owen, Woolley, Max, Fibiger, H. Christian, Bankiewicz, Krystof, Mohr, Erich

Journal:

Archives of Toxicology

Année:

2018

Langue:

english

Fichier:

PDF, 2.02 MB

english, 2018

35

SAE Technical Paper Series [SAE International Government/Industry Meeting - (APR. 26, 1999)] SAE Technical Paper Series - Progress in Understanding the Toxicity of Gasoline and Diesel Engine Exhaust Emissions

Nikula, Kristen J., Finch, Gregory L., Westhouse, Richard A., Seagrave, JeanClare, Mauderly, Joe L., Lawson, Douglas R., Gurevich, Michael

Année:

1999

Langue:

english

Fichier:

PDF, 200 KB

english, 1999

36

Structural, functional, and molecular characterization of the SHHF model of heart failure

Heyen, Jonathan R. R., Blasi, Eileen R., Nikula, Kristen, Rocha, Ricardo, Daust, Heather A., Frierdich, Gregory, Van Vleet, John F., De Ciechi, Pam, McMahon, Ellen G., Rudolph, Amy E.

Journal:

American journal of physiology. Heart and circulatory physiology

Année:

2002

Langue:

english

Fichier:

PDF, 437 KB

english, 2002

37

Long-Term Nonclinical Pulmonary Safety Assessment of Afrezza, a Novel Insulin Inhalation Powder

Greene, Stephanie F., Nikula, Kristen J., Poulin, Dominic, McInally, Kevin, Reynolds, Jack A.

Journal:

Toxicologic Pathology

Année:

2020

Fichier:

PDF, 408 KB

2020